Calnexin anticorps
Aperçu rapide pour Calnexin anticorps (ABIN6296055)
Antigène
Voir toutes Calnexin (CANX) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human Calnexin Antibody [Sodium Azide Free]
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Specificité
- Cytoplasmic
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Purification
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
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Immunogène
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
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Indications d'application
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WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/10^6 cells
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Calnexin (CANX)
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Autre désignation
- Calnexin
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Sujet
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Target Description: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Gene Symbol: CANX
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ID gène
- 821
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UniProt
- P27824
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Pathways
- Signalisation MAPK, Thyroid Hormone Synthesis
Antigène
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